Septerna (SEPN) Stock Analysis & Price (Updated Oct 16, 2026, 4:00 PM ET)
Updated Oct 16, 2026, 4:00 PM ET
- Closed at $36.35, -2.94% vs the prior close of $37.45.
- Volume 234.12K shares, 0.6x its 50-day average (light).
- No new SEC filings since the prior session.
- No new insider buys or sales reported since the prior session.
SEPN dips 2.9% to $36.35. Closed at $36.35, -2.94% vs the prior close of $37.45. Day range $35.09–$37.47, opened at $37.47.
SEPN daily analysis — what happened
A plain-English, data-only note written after every US trading day. Newest first; older days stay archived below.
Oct 16, 2026 — SEPN dips 2.9% to $36.35
- Closed at $36.35, -2.94% vs the prior close of $37.45. Day range $35.09–$37.47, opened at $37.47.
- Volume was 234.12K shares, 0.6x its 50-day average of 416.58K — lighter than usual.
- Price is -7.6% vs its 50-day average ($39.34) and +16.1% vs its 200-day average ($31.31).
- 52-week range $17.55–$51.10; today's close sits at 56% of that range, 28.9% below the 52-week high.
Oct 15, 2026 — SEPN jumps 3.1% to $37.45
- Closed at $37.45, +3.11% vs the prior close of $36.32. Day range $36.22–$38.36, opened at $36.78.
- Volume was 271.40K shares, 0.6x its 50-day average of 420.01K.
- Price is -5.0% vs its 50-day average ($39.40) and +19.8% vs its 200-day average ($31.27).
- 52-week range $17.55–$51.10; today's close sits at 59% of that range, 26.7% below the 52-week high.
Oct 14, 2026 — SEPN ends flat (-0.3%) to $36.32, 3 down days in a row
- Closed at $36.32, -0.26% vs the prior close of $36.42. Day range $34.36–$37.28, opened at $36.00.
- Volume was 370.00K shares, 0.9x its 50-day average of 420.58K.
- Price is -7.9% vs its 50-day average ($39.43) and +16.3% vs its 200-day average ($31.23).
- 52-week range $17.55–$51.10; today's close sits at 56% of that range, 28.9% below the 52-week high.
- That makes 3 straight losses.
Oct 13, 2026 — SEPN slides 3.0% to $36.42
- Closed at $36.42, -3.05% vs the prior close of $37.56. Day range $36.28–$38.51, opened at $37.49.
- Volume was 491.90K shares, 1.2x its 50-day average of 414.78K.
- Price is -7.8% vs its 50-day average ($39.48) and +16.8% vs its 200-day average ($31.19).
- 52-week range $17.55–$51.10; today's close sits at 56% of that range, 28.7% below the 52-week high.
Oct 12, 2026 — SEPN dips 2.1% to $37.56
- Closed at $37.56, -2.11% vs the prior close of $38.37. Day range $37.25–$38.41, opened at $38.32.
- Volume was 207.60K shares, 0.5x its 50-day average of 415.45K — lighter than usual.
- Price is -4.8% vs its 50-day average ($39.45) and +20.6% vs its 200-day average ($31.15).
- 52-week range $17.55–$51.10; today's close sits at 60% of that range, 26.5% below the 52-week high.
Oct 9, 2026 — SEPN jumps 4.0% to $38.37, 3 up days in a row
- Closed at $38.37, +3.98% vs the prior close of $36.90. Day range $35.76–$38.73, opened at $36.76.
- Volume was 349.40K shares, 0.8x its 50-day average of 413.75K.
- Price is -2.6% vs its 50-day average ($39.39) and +23.4% vs its 200-day average ($31.11).
- 52-week range $17.55–$51.10; today's close sits at 62% of that range, 24.9% below the 52-week high.
- That makes 3 straight gains.
Oct 8, 2026 — SEPN rises 2.5% to $36.90 on 1.9x normal volume
- Closed at $36.90, +2.50% vs the prior close of $36.00. Day range $34.66–$37.09, opened at $35.47.
- Volume was 745.40K shares, 1.9x its 50-day average of 402.01K — unusually heavy trading.
- Price is -6.2% vs its 50-day average ($39.33) and +18.8% vs its 200-day average ($31.06).
- 52-week range $17.55–$51.10; today's close sits at 58% of that range, 27.8% below the 52-week high.
Oct 7, 2026 — SEPN rises 0.9% to $36.00 on 2.7x normal volume
- Closed at $36.00, +0.93% vs the prior close of $35.67. Day range $35.20–$37.14, opened at $35.27.
- Volume was 1.03M shares, 2.7x its 50-day average of 386.71K — unusually heavy trading.
- Price is -8.3% vs its 50-day average ($39.26) and +16.0% vs its 200-day average ($31.02).
- 52-week range $17.55–$51.10; today's close sits at 55% of that range, 29.5% below the 52-week high.
Oct 6, 2026 — SEPN slides 5.8% to $35.67, a 1-month low
- Closed at $35.67, -5.81% vs the prior close of $37.87. Day range $35.60–$38.69, opened at $37.97.
- Volume was 490.40K shares, 1.3x its 50-day average of 379.78K.
- Price is -9.1% vs its 50-day average ($39.22) and +15.1% vs its 200-day average ($30.98).
- 52-week range $17.55–$51.10; today's close sits at 54% of that range, 30.2% below the 52-week high.
Oct 5, 2026 — SEPN rises 0.4% to $37.87
- Closed at $37.87, +0.42% vs the prior close of $37.71. Day range $36.82–$38.52, opened at $37.83.
- Volume was 266.70K shares, 0.7x its 50-day average of 379.29K.
- Price is -3.3% vs its 50-day average ($39.18) and +22.4% vs its 200-day average ($30.94).
- 52-week range $17.55–$51.10; today's close sits at 61% of that range, 25.9% below the 52-week high.
Oct 2, 2026 — SEPN dips 0.9% to $37.71, 4 down days in a row
- Closed at $37.71, -0.89% vs the prior close of $38.05. Day range $37.31–$39.10, opened at $38.84.
- Volume was 395.40K shares, 1.0x its 50-day average of 377.34K.
- Price is -3.5% vs its 50-day average ($39.08) and +22.1% vs its 200-day average ($30.88).
- 52-week range $17.55–$51.10; today's close sits at 60% of that range, 26.2% below the 52-week high.
- That makes 4 straight losses.
SEPN latest news & SEC filings
Every SEC filing by or about SEPN in the last 120 days, explained in plain English. Updated daily, with a same-day refresh for new filings.
Oct 1, 2026 · Form 144 — Planned insider sale
Notice of proposed sale (Form 144) — an insider or affiliate plans to sell restricted or control shares
A notice of intent, not a completed sale. Any actual sale by a director or officer shows up later on Form 4.
Oct 1, 2026 · Form 144 — Planned insider sale
Notice of proposed sale (Form 144) — an insider or affiliate plans to sell restricted or control shares
A notice of intent, not a completed sale. Any actual sale by a director or officer shows up later on Form 4.
Sep 10, 2026 · Form 4 — Insider trade
Insider trade report (Form 4) — a director, officer or 10%+ owner changed their holdings
Insider holdings update with no common-stock transactions in the table (often options or derivative awards only).
Sep 3, 2026 · Form 3 — New insider holdings
Initial insider ownership statement (Form 3) — a new director, officer or 10% owner disclosed their holdings
Sep 3, 2026 · Form 4 — Insider trade
Insider trade report (Form 4) — a director, officer or 10%+ owner changed their holdings
- Long Daniel D. sold 3,333 shares at $37.83 (≈$126.09K) on Sep 1, 2026
- Long Daniel D. sold 3,333 shares at $37.83 (≈$126.09K) on Sep 1, 2026
- Long Daniel D. sold 3,333 shares at $37.83 (≈$126.09K) on Sep 1, 2026
- Long Daniel D. sold 3,333 shares at $37.83 (≈$126.09K) on Sep 1, 2026
Open-market purchases (P) and sales (S) are shown in colour; awards, exercises and tax withholding are routine pay-related moves. Many sales are pre-planned under 10b5-1 plans.
Aug 25, 2026 · Form 8-K — Major event / current report
Current report — a filing companies must make within 4 business days of a major event
- Item 7.01 — Released information under Regulation FD (e.g. a presentation or press release).
- Item 8.01 — Reported other events the company considers important.
Aug 14, 2026 · Form 4 — Insider trade
Insider trade report (Form 4) — a director, officer or 10%+ owner changed their holdings
- Third Rock Ventures Gp Vi, L.P. sold 141 shares at $51.08 (≈$7.20K) on Aug 12, 2026
- Third Rock Ventures Gp Vi, L.P. sold 147,059 shares at $50.27 (≈$7.39M) on Aug 12, 2026
- Third Rock Ventures Gp Vi, L.P. sold 141 shares at $51.08 (≈$7.20K) on Aug 12, 2026
- Third Rock Ventures Gp Vi, L.P. sold 147,059 shares at $50.27 (≈$7.39M) on Aug 12, 2026
- Third Rock Ventures V, L.P. sold 141 shares at $51.08 (≈$7.20K) on Aug 12, 2026
- Third Rock Ventures V, L.P. sold 147,059 shares at $50.27 (≈$7.39M) on Aug 12, 2026
- …plus 15 more transaction lines in the filing.
Open-market purchases (P) and sales (S) are shown in colour; awards, exercises and tax withholding are routine pay-related moves. Many sales are pre-planned under 10b5-1 plans.
Aug 14, 2026 · Form SCHEDULE 13D/A — Update to a 13D 5%+ stake disclosure
Update to a 13D 5%+ stake disclosure
Filed by an outside investor (not the company). It reports a holding of more than 5% of a share class; percentage and holder name are in the filing.
Aug 14, 2026 · Form SCHEDULE 13G/A — Update to a passive 5%+ stake (13G)
Update to a passive 5%+ stake (13G)
Filed by an outside investor (not the company). It reports a holding of more than 5% of a share class; percentage and holder name are in the filing.
Aug 10, 2026 · Form 10-Q — Quarterly report
Quarterly report (unaudited financial statements for the quarter)
Quarter ended Jun 30, 2026:
- Revenue: $26.75M (prior year $119.00K) (+22375.6% vs Jun 30, 2025)
- Net income: -$13.03M (prior year -$24.84M) (loss narrowed vs Jun 30, 2025)
- Diluted EPS: -$0.29 (prior year -$0.56) (loss narrowed vs Jun 30, 2025)
Aug 10, 2026 · Form 8-K — Major event / current report
Current report — a filing companies must make within 4 business days of a major event
- Item 2.02 — Reported results of operations (earnings release).
This is a results-day filing: the earnings press release is attached as an exhibit.
Jun 30, 2026 · Form 8-K — Major event / current report
Current report — a filing companies must make within 4 business days of a major event
- Item 5.07 — Reported shareholder vote results.
Things to know before you trade SEPN
- Last results release: Aug 10, 2026 (8-K Item 2.02). Previous ones: May 11, 2026, Mar 9, 2026, Nov 10, 2025. Based on that rhythm, the next report is likely around Nov 9, 2026 — an estimate, not a confirmed date.
- How much it moves: over the last 20 sessions the average daily move was 2.36% (largest 5.8%).
- Liquidity: about 415.98K shares (≈$15.12M) trade per day on average.
- 52-week position: $36.35 vs a range of $17.55–$51.10 (56% of the range).
- Dividends: no cash dividends in the last 2 years.
- Splits: none in the last 2 years.
- Insider trades (Form 4, last 12 months, recent 25 shown): 0 open-market buys, 25 sales; latest: Daniel D. Long sold 3,333 shares on Sep 1, 2026.
- Latest filings: 8-K Aug 25, 2026; 10-Q Aug 10, 2026; 8-K Aug 10, 2026.
- Share count: 46.68M shares outstanding (Aug 5, 2026), +4.7% vs a year earlier.
- Listing: Nasdaq · industry: Pharmaceutical Preparations.
SEPN market data (last 20 sessions)
| Date | Open | High | Low | Close | Volume |
|---|---|---|---|---|---|
| Oct 16, 2026 | 37.47 | 37.47 | 35.09 | 36.35 | 234.12K |
| Oct 15, 2026 | 36.78 | 38.36 | 36.22 | 37.45 | 271.40K |
| Oct 14, 2026 | 36.00 | 37.28 | 34.36 | 36.32 | 370.00K |
| Oct 13, 2026 | 37.49 | 38.51 | 36.28 | 36.42 | 491.90K |
| Oct 12, 2026 | 38.32 | 38.41 | 37.25 | 37.56 | 207.60K |
| Oct 9, 2026 | 36.76 | 38.73 | 35.76 | 38.37 | 349.40K |
| Oct 8, 2026 | 35.47 | 37.09 | 34.66 | 36.90 | 745.40K |
| Oct 7, 2026 | 35.27 | 37.14 | 35.20 | 36.00 | 1.03M |
| Oct 6, 2026 | 37.97 | 38.69 | 35.60 | 35.67 | 490.40K |
| Oct 5, 2026 | 37.83 | 38.52 | 36.82 | 37.87 | 266.70K |
| Oct 2, 2026 | 38.84 | 39.10 | 37.31 | 37.71 | 395.40K |
| Oct 1, 2026 | 38.90 | 39.52 | 37.81 | 38.05 | 545.10K |
| Sep 30, 2026 | 39.13 | 39.85 | 38.49 | 39.13 | 209.60K |
| Sep 29, 2026 | 39.52 | 39.56 | 38.37 | 39.13 | 564.50K |
| Sep 28, 2026 | 37.61 | 39.78 | 37.03 | 39.74 | 338.30K |
| Sep 25, 2026 | 38.34 | 38.34 | 37.35 | 37.77 | 344.30K |
| Sep 24, 2026 | 38.41 | 38.81 | 37.49 | 38.13 | 293.00K |
| Sep 23, 2026 | 40.17 | 40.17 | 36.98 | 38.45 | 509.70K |
| Sep 22, 2026 | 38.78 | 41.09 | 38.74 | 40.38 | 412.00K |
| Sep 21, 2026 | 38.97 | 39.47 | 38.01 | 38.54 | 252.40K |
About Septerna
Septerna (SEPN) is listed on the Nasdaq and classified by the SEC under “Pharmaceutical Preparations”. Its business address is in SOUTH SAN FRANCISCO, CA. State of incorporation: DE. Fiscal year ends December 31. SEC CIK 1984086.
SEPN board of directors & executives
From SEC Form 3/4/5 insider filings made in the last 12 months (date = latest filing).
Directors
| Name | Role | Latest filing |
|---|---|---|
| Abraham Bassan | Director | Jun 30, 2026 |
| Bernard Coulie | Director | Jun 30, 2026 |
| Alan Ezekowitz | Director | Jun 30, 2026 |
| Jeffrey Finer | Chief Executive Officer | Feb 10, 2026 |
| Keith Michael Gottesdiener | Director | Jun 30, 2026 |
| Peter Kolchinsky | Director | Aug 14, 2026 |
| Capital Management, L.P. Ra | Director | Aug 14, 2026 |
| Capital Healthcare Fund Lp Ra | Director | Aug 14, 2026 |
| Capital Nexus Fund Iii, L.P. Ra | Director | Aug 14, 2026 |
| Rajeev M. Shah | Director | Aug 14, 2026 |
| Shalini Sharp | Director | Jun 30, 2026 |
| Jake Simson | Director | Jun 30, 2026 |
| Jeffrey K Tong | Director | Jun 30, 2026 |
Executive officers
| Name | Title | Latest filing |
|---|---|---|
| Elizabeth Bhatt | President and COO | Aug 13, 2026 |
| Jeffrey Finer | Chief Executive Officer | Feb 10, 2026 |
| Jae B. Kim | Chief Medical Officer | Feb 10, 2026 |
| Uwe Klein | SVP, Biological Sciences | Feb 10, 2026 |
| Gil M Labrucherie | Chief Financial Officer | Feb 10, 2026 |
| Daniel D. Long | SVP, Drug Discovery | Sep 3, 2026 |
| Rajiv Patni | Chief Medical Officer | Sep 10, 2026 |
| Samira Shaikhly | Chief People Officer | Jun 30, 2026 |
| Mark Andrew Wilson | Chief Legal Officer | Feb 10, 2026 |
Recent insider buys & sales
| Date | Insider | Type | Shares | Price |
|---|---|---|---|---|
| Sep 1, 2026 | Daniel D. Long | Sale | 3,333 | $37.83 |
| Sep 1, 2026 | Daniel D. Long | Sale | 3,333 | $37.83 |
| Sep 1, 2026 | Daniel D. Long | Sale | 3,333 | $37.83 |
| Sep 1, 2026 | Daniel D. Long | Sale | 3,333 | $37.83 |
| Aug 12, 2026 | Rock Ventures Gp Vi, L.P. Third | Sale | 141 | $51.08 |
| Aug 12, 2026 | Rock Ventures Gp Vi, L.P. Third | Sale | 147,059 | $50.27 |
| Aug 12, 2026 | Rock Ventures Gp Vi, L.P. Third | Sale | 141 | $51.08 |
| Aug 12, 2026 | Rock Ventures Gp Vi, L.P. Third | Sale | 147,059 | $50.27 |
| Aug 12, 2026 | Rock Ventures V, L.P. Third | Sale | 141 | $51.08 |
| Aug 12, 2026 | Rock Ventures V, L.P. Third | Sale | 147,059 | $50.27 |
| Aug 12, 2026 | Rock Ventures V, L.P. Third | Sale | 141 | $51.08 |
| Aug 12, 2026 | Rock Ventures V, L.P. Third | Sale | 147,059 | $50.27 |
| Aug 12, 2026 | Rock Ventures Gp V, Lp Third | Sale | 141 | $51.08 |
| Aug 12, 2026 | Rock Ventures Gp V, Lp Third | Sale | 147,059 | $50.27 |
| Aug 12, 2026 | Rock Ventures Gp V, Lp Third | Sale | 141 | $51.08 |
SEPN financials (annual, from XBRL filings)
| Fiscal year end | Revenue | Net income | Diluted EPS | Operating cash flow |
|---|---|---|---|---|
| Dec 31, 2025 | $45.95M | $-48.88M | -1.10 | $110.19M |
| Dec 31, 2024 | $1.07M | $-71.80M | -7.26 | $-67.47M |
| Dec 31, 2023 | $151.00K | $4.18M | 0.29 | $-38.72M |
Latest balance sheet: total assets $566.74M, total liabilities $180.02M, cash $84.66M (as of Jun 30, 2026).
SEPN earnings / results-day log
| Date | Filing | Close that day |
|---|---|---|
| Aug 10, 2026 | 8-K Item 2.02 (results) | $38.85 |
| May 11, 2026 | 8-K Item 2.02 (results) | $23.57 |
| Mar 9, 2026 | 8-K Item 2.02 (results) | $29.06 |
| Nov 10, 2025 | 8-K Item 2.02 (results) | $18.10 |
| Aug 11, 2025 | 8-K Item 2.02 (results) | $11.49 |
| May 15, 2025 | 8-K Item 2.02 (results) | $10.12 |
| Mar 27, 2025 | 8-K Item 2.02 (results) | $6.29 |
| Nov 20, 2024 | 8-K Item 2.02 (results) | $22.50 |
Related stocks · Pharmaceutical Preparations
Eli Lilly (LLY)Johnson & Johnson (JNJ)Merck (MRK)AbbVie (ABBV)Abbott Laboratories (ABT)Pfizer (PFE)Bristol Myers Squibb (BMY)Vertex Pharmaceuticals Inc / Ma (VRTX)Novo Nordisk A S (NVO)Regeneron Pharmaceuticals (REGN)
Popular today
Spdr S&P 500 Etf (SPY)Micron Technology (MU)Nvidia (NVDA)Meta Platforms (META)Sandisk (SNDK)AMD (AMD)Space Exploration Technologies (SPCX)Tesla (TSLA)Apple (AAPL)Intel (INTC)Microsoft (MSFT)Amazon (AMZN)
More on SEPN
Information only, not investment advice. BuyMeWhiskey is not a registered investment adviser or broker-dealer; nothing here is a recommendation to buy, sell or hold any security, and there are no price targets. Data comes from SEC EDGAR filings and public end-of-day market data and may be delayed or contain errors. Verify with the company's filings before making decisions. Prices: end-of-day data as of Oct 16, 2026, 4:00 PM ET. Filings: SEC EDGAR. Updated after every US trading day.