Praxis Precision Medicines (PRAX) Stock: Why It's Up Today
Updated Oct 19, 2026, 12:05 PM ET · intraday price
- Trading at $257.11 as of 12:05 PM ET, +6.35% vs the prior close of $241.76.
- Volume 141.54K shares, 0.3x its 50-day average (light).
- No new SEC filings since the prior session.
- No new insider buys or sales reported since the prior session.
PRAX jumps 6.3% to $257.11. Trading at $257.11 (intraday, 12:05 PM ET), +6.35% vs the prior close of $241.76. Day range $244.26–$258.45, opened at $245.42.
PRAX daily analysis — what happened
A plain-English, data-only note for every US trading day (today's note updates every 2 hours while the market is open). Newest first; older days stay archived below.
Oct 19, 2026 — PRAX jumps 6.3% to $257.11
- Trading at $257.11 (intraday, 12:05 PM ET), +6.35% vs the prior close of $241.76. Day range $244.26–$258.45, opened at $245.42.
- Volume was 141.54K shares, 0.3x its 50-day average of 442.66K — lighter than usual.
- Price is -19.6% vs its 50-day average ($319.79) and -18.5% vs its 200-day average ($315.51).
- 52-week range $154.45–$392.70; the current price sits at 43% of that range, 34.5% below the 52-week high.
Oct 16, 2026 — PRAX dips 2.6% to $241.76
- Closed at $241.76, -2.61% vs the prior close of $248.24. Day range $241.76–$251.78, opened at $250.11.
- Volume was 502.61K shares, 1.1x its 50-day average of 461.96K.
- Price is -24.9% vs its 50-day average ($321.87) and -23.4% vs its 200-day average ($315.70).
- 52-week range $154.45–$392.70; today's close sits at 37% of that range, 38.4% below the 52-week high.
Oct 15, 2026 — PRAX jumps 3.9% to $248.24
- Closed at $248.24, +3.86% vs the prior close of $239.02. Day range $239.90–$255.42, opened at $245.28.
- Volume was 632.80K shares, 1.4x its 50-day average of 454.80K.
- Price is -23.5% vs its 50-day average ($324.43) and -21.4% vs its 200-day average ($315.98).
- 52-week range $52.62–$392.70; today's close sits at 58% of that range, 36.8% below the 52-week high.
Oct 14, 2026 — PRAX dips 1.8% to $239.02, a 6-month low on 2.2x normal volume
- Closed at $239.02, -1.78% vs the prior close of $243.34. Day range $236.79–$245.57, opened at $239.72.
- Volume was 958.70K shares, 2.2x its 50-day average of 442.17K — unusually heavy trading.
- Price is -26.6% vs its 50-day average ($325.85) and -24.4% vs its 200-day average ($316.26).
- 52-week range $50.56–$392.70; today's close sits at 55% of that range, 39.1% below the 52-week high.
- That makes 8 straight losses.
Oct 13, 2026 — PRAX slides 3.2% to $243.34, a 3-month low, 7 down days in a row
- Closed at $243.34, -3.20% vs the prior close of $251.38. Day range $241.53–$252.64, opened at $250.09.
- Volume was 622.20K shares, 1.4x its 50-day average of 436.02K.
- Price is -25.6% vs its 50-day average ($327.28) and -23.1% vs its 200-day average ($316.41).
- 52-week range $50.56–$392.70; today's close sits at 56% of that range, 38.0% below the 52-week high.
- That makes 7 straight losses.
Oct 12, 2026 — PRAX slides 3.3% to $251.38, a 3-month low, 6 down days in a row
- Closed at $251.38, -3.26% vs the prior close of $259.86. Day range $251.21–$259.50, opened at $257.94.
- Volume was 301.30K shares, 0.7x its 50-day average of 437.70K.
- Price is -23.5% vs its 50-day average ($328.52) and -20.6% vs its 200-day average ($316.57).
- 52-week range $50.56–$392.70; today's close sits at 59% of that range, 36.0% below the 52-week high.
- That makes 6 straight losses.
Oct 9, 2026 — PRAX dips 1.4% to $259.86, a 3-month low, 5 down days in a row
- Closed at $259.86, -1.40% vs the prior close of $263.55. Day range $259.00–$267.85, opened at $266.91.
- Volume was 517.20K shares, 1.2x its 50-day average of 437.68K.
- Price is -21.2% vs its 50-day average ($329.65) and -17.9% vs its 200-day average ($316.69).
- 52-week range $50.56–$392.70; today's close sits at 61% of that range, 33.8% below the 52-week high.
- That makes 5 straight losses.
Oct 8, 2026 — PRAX slides 5.2% to $263.55, a 3-month low, 4 down days in a row
- Closed at $263.55, -5.20% vs the prior close of $278.02. Day range $260.07–$273.96, opened at $273.74.
- Volume was 675.60K shares, 1.6x its 50-day average of 430.97K.
- Price is -20.3% vs its 50-day average ($330.61) and -16.8% vs its 200-day average ($316.79).
- 52-week range $50.56–$392.70; today's close sits at 62% of that range, 32.9% below the 52-week high.
- That makes 4 straight losses.
Oct 7, 2026 — PRAX dips 0.8% to $278.02, a 3-month low, 3 down days in a row
- Closed at $278.02, -0.76% vs the prior close of $280.14. Day range $271.28–$285.63, opened at $277.16.
- Volume was 444.20K shares, 1.0x its 50-day average of 430.85K.
- Price is -16.0% vs its 50-day average ($331.15) and -12.3% vs its 200-day average ($316.84).
- 52-week range $50.31–$392.70; today's close sits at 67% of that range, 29.2% below the 52-week high.
- That makes 3 straight losses.
Oct 6, 2026 — PRAX dips 1.2% to $280.14, a 3-month low
- Closed at $280.14, -1.21% vs the prior close of $283.56. Day range $272.17–$289.47, opened at $289.47.
- Volume was 435.20K shares, 1.0x its 50-day average of 428.07K.
- Price is -15.5% vs its 50-day average ($331.51) and -11.6% vs its 200-day average ($316.79).
- 52-week range $50.31–$392.70; today's close sits at 67% of that range, 28.7% below the 52-week high.
Oct 5, 2026 — PRAX slides 4.0% to $283.56
- Closed at $283.56, -4.04% vs the prior close of $295.51. Day range $278.01–$299.12, opened at $299.12.
- Volume was 511.10K shares, 1.2x its 50-day average of 423.50K.
- Price is -14.6% vs its 50-day average ($332.22) and -10.5% vs its 200-day average ($316.72).
- 52-week range $50.31–$392.70; today's close sits at 68% of that range, 27.8% below the 52-week high.
Oct 2, 2026 — PRAX rises 3.0% to $295.51
- Closed at $295.51, +3.00% vs the prior close of $286.91. Day range $286.00–$298.56, opened at $290.13.
- Volume was 456.10K shares, 1.1x its 50-day average of 420.89K.
- Price is -11.3% vs its 50-day average ($333.06) and -6.7% vs its 200-day average ($316.68).
- 52-week range $50.31–$392.70; today's close sits at 72% of that range, 24.7% below the 52-week high.
PRAX bull case vs bear case (from the data)
- No clear positive signal in the price trend, filings or insider data right now.
- Price is -19.6% vs its 50-day average — short-term trend is down.
- Price is -18.5% vs its 200-day average — below the long-term trend line.
- Annual revenue fell 100.0% in the latest fiscal year (SEC XBRL).
- Latest fiscal-year net income: loss of $303.27M.
- Insider selling outweighs buying: 25 sales vs 0 open-market buys among the 25 most recent reported insider trades (Form 4, last 12 months).
- Share count up 32.7% in a year (dilution).
PRAX latest news & SEC filings
Every SEC filing by or about PRAX in the last 120 days, explained in plain English. Updated daily, with a same-day refresh for new filings.
Aug 14, 2026 · Form SCHEDULE 13G/A — Update to a passive 5%+ stake (13G)
Update to a passive 5%+ stake (13G)
Filed by an outside investor (not the company). It reports a holding of more than 5% of a share class; percentage and holder name are in the filing.
Aug 6, 2026 · Form 10-Q — Quarterly report
Quarterly report (unaudited financial statements for the quarter)
Quarter ended Jun 30, 2026:
- Net income: -$83.72M (prior year -$71.13M) (loss widened vs Jun 30, 2025)
- Diluted EPS: -$2.87 (prior year -$3.31) (loss narrowed vs Jun 30, 2025)
Aug 6, 2026 · Form 8-K — Major event / current report
Current report — a filing companies must make within 4 business days of a major event
- Item 2.02 — Reported results of operations (earnings release).
- Item 7.01 — Released information under Regulation FD (e.g. a presentation or press release).
This is a results-day filing: the earnings press release is attached as an exhibit.
Jul 8, 2026 · Form 4 — Insider trade
Insider trade report (Form 4) — a director, officer or 10%+ owner changed their holdings
Insider holdings update with no common-stock transactions in the table (often options or derivative awards only).
Jul 7, 2026 · Form 8-K — Major event / current report
Current report — a filing companies must make within 4 business days of a major event
- Item 8.01 — Reported other events the company considers important.
Jul 2, 2026 · Form 8-K — Major event / current report
Current report — a filing companies must make within 4 business days of a major event
- Item 4.01 — Changed its outside auditor.
Jun 29, 2026 · Form 8-K — Major event / current report
Current report — a filing companies must make within 4 business days of a major event
- Item 8.01 — Reported other events the company considers important.
Jun 26, 2026 · Form 4 — Insider trade
Insider trade report (Form 4) — a director, officer or 10%+ owner changed their holdings
- Desimone Jill sold 10 shares at $301.44 (≈$3.01K) on Jun 24, 2026
- Desimone Jill sold 1,279 shares at $314.90 (≈$402.76K) on Jun 24, 2026
- Desimone Jill sold 837 shares at $315.71 (≈$264.25K) on Jun 24, 2026
- Desimone Jill sold 504 shares at $313.66 (≈$158.08K) on Jun 24, 2026
- Desimone Jill sold 1,004 shares at $312.83 (≈$314.08K) on Jun 24, 2026
- Desimone Jill sold 2,854 shares at $311.91 (≈$890.19K) on Jun 24, 2026
- …plus 19 more transaction lines in the filing.
Open-market purchases (P) and sales (S) are shown in colour; awards, exercises and tax withholding are routine pay-related moves. Many sales are pre-planned under 10b5-1 plans.
Jun 24, 2026 · Form 144 — Planned insider sale
Notice of proposed sale (Form 144) — an insider or affiliate plans to sell restricted or control shares
A notice of intent, not a completed sale. Any actual sale by a director or officer shows up later on Form 4.
Jun 22, 2026 · Form 8-K — Major event / current report
Current report — a filing companies must make within 4 business days of a major event
- Item 8.01 — Reported other events the company considers important.
Things to know before you trade PRAX
- Last results release: Aug 6, 2026 (8-K Item 2.02). Previous ones: May 7, 2026, Feb 19, 2026, Jan 6, 2026. Based on that rhythm, the next report is likely around Nov 5, 2026 — an estimate, not a confirmed date.
- How much it moves: over the last 20 sessions the average daily move was 2.62% (largest 6.3%).
- Liquidity: about 534.47K shares (≈$137.41M) trade per day on average.
- 52-week position: $257.11 vs a range of $154.45–$392.70 (43% of the range).
- Dividends: no cash dividends in the last 2 years.
- Splits: none in the last 2 years.
- Insider trades (Form 4, last 12 months, recent 25 shown): 0 open-market buys, 25 sales; latest: Jill Desimone sold 10 shares on Jun 24, 2026.
- Latest filings: 10-Q Aug 6, 2026; 8-K Aug 6, 2026; 8-K Jul 7, 2026.
- Share count: 27.92M shares outstanding (Jul 31, 2026), +32.7% vs a year earlier — notable dilution.
- Listing: Nasdaq · industry: Pharmaceutical Preparations.
PRAX market data (last 20 sessions)
| Date | Open | High | Low | Close | Volume |
|---|---|---|---|---|---|
| Oct 19, 2026 | 245.42 | 258.45 | 244.26 | 257.11 | 141.54K |
| Oct 16, 2026 | 250.11 | 251.78 | 241.76 | 241.76 | 541.80K |
| Oct 15, 2026 | 245.28 | 255.42 | 239.90 | 248.24 | 632.80K |
| Oct 14, 2026 | 239.72 | 245.57 | 236.79 | 239.02 | 958.70K |
| Oct 13, 2026 | 250.09 | 252.64 | 241.53 | 243.34 | 622.20K |
| Oct 12, 2026 | 257.94 | 259.50 | 251.21 | 251.38 | 301.30K |
| Oct 9, 2026 | 266.91 | 267.85 | 259.00 | 259.86 | 517.20K |
| Oct 8, 2026 | 273.74 | 273.96 | 260.07 | 263.55 | 675.60K |
| Oct 7, 2026 | 277.16 | 285.63 | 271.28 | 278.02 | 444.20K |
| Oct 6, 2026 | 289.47 | 289.47 | 272.17 | 280.14 | 435.20K |
| Oct 5, 2026 | 299.12 | 299.12 | 278.01 | 283.56 | 511.10K |
| Oct 2, 2026 | 290.13 | 298.56 | 286.00 | 295.51 | 456.10K |
| Oct 1, 2026 | 287.83 | 292.47 | 282.00 | 286.91 | 381.60K |
| Sep 30, 2026 | 284.65 | 296.27 | 282.00 | 291.23 | 710.60K |
| Sep 29, 2026 | 283.28 | 289.15 | 278.39 | 281.00 | 349.60K |
| Sep 28, 2026 | 280.78 | 292.18 | 277.90 | 285.65 | 436.70K |
| Sep 25, 2026 | 284.45 | 289.05 | 278.60 | 280.78 | 462.20K |
| Sep 24, 2026 | 281.18 | 286.38 | 276.34 | 281.79 | 535.40K |
| Sep 23, 2026 | 301.37 | 304.93 | 275.89 | 282.12 | 1.01M |
| Sep 22, 2026 | 300.19 | 312.46 | 298.40 | 300.65 | 570.20K |
About Praxis Precision Medicines
Praxis Precision Medicines (PRAX) is listed on the Nasdaq and classified by the SEC under “Pharmaceutical Preparations”. Its business address is in BOSTON, MA. State of incorporation: DE. Fiscal year ends December 31. SEC CIK 1689548.
PRAX board of directors & executives
From SEC Form 3/4/5 insider filings made in the last 12 months (date = latest filing).
Directors
| Name | Role | Latest filing |
|---|---|---|
| Stuart A Arbuckle | Director | Jun 12, 2026 |
| Jeffrey Chodakewitz | Director | Jun 12, 2026 |
| Merit Ester Cudkowicz | Director | Jun 12, 2026 |
| Jill Desimone | Director | Jun 26, 2026 |
| Jeffrey B Kindler | Director | Jun 12, 2026 |
| Dean J Mitchell | Director | Jun 12, 2026 |
| Gregory Norden | Director | Jun 12, 2026 |
| Marcio Souza | Chief Executive Officer | Jul 8, 2026 |
| William D Young | Director | Jun 12, 2026 |
Executive officers
| Name | Title | Latest filing |
|---|---|---|
| Timothy Edwin Kelly | Chief Financial Officer | May 19, 2026 |
| Lauren Mastrocola | Principal Accounting Officer | May 19, 2026 |
| Alex Nemiroff | General Counsel and Secretary | May 19, 2026 |
| Megan Sniecinski | Chief Operating Officer | May 19, 2026 |
| Marcio Souza | Chief Executive Officer | Jul 8, 2026 |
Recent insider buys & sales
| Date | Insider | Type | Shares | Price |
|---|---|---|---|---|
| Jun 24, 2026 | Jill Desimone | Sale | 10 | $301.44 |
| Jun 24, 2026 | Jill Desimone | Sale | 1,279 | $314.90 |
| Jun 24, 2026 | Jill Desimone | Sale | 837 | $315.71 |
| Jun 24, 2026 | Jill Desimone | Sale | 504 | $313.66 |
| Jun 24, 2026 | Jill Desimone | Sale | 1,004 | $312.83 |
| Jun 24, 2026 | Jill Desimone | Sale | 2,854 | $311.91 |
| Jun 24, 2026 | Jill Desimone | Sale | 1,750 | $310.89 |
| Jun 24, 2026 | Jill Desimone | Sale | 999 | $309.38 |
| Jun 24, 2026 | Jill Desimone | Sale | 1,240 | $308.24 |
| Jun 24, 2026 | Jill Desimone | Sale | 683 | $306.77 |
| Jun 24, 2026 | Jill Desimone | Sale | 320 | $305.31 |
| Jun 24, 2026 | Jill Desimone | Sale | 120 | $303.13 |
| Jun 24, 2026 | Jill Desimone | Sale | 10 | $301.44 |
| Jun 24, 2026 | Jill Desimone | Sale | 1,279 | $314.90 |
| Jun 24, 2026 | Jill Desimone | Sale | 837 | $315.71 |
PRAX financials (annual, from XBRL filings)
| Fiscal year end | Revenue | Net income | Diluted EPS | Operating cash flow |
|---|---|---|---|---|
| Dec 31, 2025 | $0 | $-303.27M | -13.48 | $-249.07M |
| Dec 31, 2024 | $8.55M | $-182.82M | -10.21 | $-131.76M |
| Dec 31, 2023 | $2.45M | $-123.28M | -18.69 | $-111.14M |
| Dec 31, 2022 | $0 | $-214.03M | -69.65 | $-185.04M |
| Dec 31, 2021 | — | $-167.06M | -3.94 | $-124.55M |
Latest balance sheet: total assets $1.39B, total liabilities $49.06M, cash $474.76M (as of Jun 30, 2026).
PRAX earnings / results-day log
| Date | Filing | Close that day |
|---|---|---|
| Aug 6, 2026 | 8-K Item 2.02 (results) | $370.16 |
| May 7, 2026 | 8-K Item 2.02 (results) | $333.28 |
| Feb 19, 2026 | 8-K Item 2.02 (results) | $331.61 |
| Jan 6, 2026 | 8-K Item 2.02 (results) | $272.90 |
| Nov 5, 2025 | 8-K Item 2.02 (results) | $164.64 |
| Aug 4, 2025 | 8-K Item 2.02 (results) | $51.09 |
| May 2, 2025 | 8-K Item 2.02 (results) | $40.24 |
| Feb 28, 2025 | 8-K Item 2.02 (results) | $38.60 |
| Jan 29, 2025 | 8-K Item 2.02 (results) | $74.02 |
| Nov 6, 2024 | 8-K Item 2.02 (results) | $71.87 |
| Aug 13, 2024 | 8-K Item 2.02 (results) | — |
| May 13, 2024 | 8-K Item 2.02 (results) | — |
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Information only, not investment advice. BuyMeWhiskey is not a registered investment adviser or broker-dealer; nothing here is a recommendation to buy, sell or hold any security, and there are no price targets. Data comes from SEC EDGAR filings and public end-of-day market data and may be delayed or contain errors. Verify with the company's filings before making decisions. Prices: intraday data as of Oct 19, 2026, 12:05 PM ET. Filings: SEC EDGAR. Refreshed every 2 hours during US market hours.