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Nasdaq · IONS

Ionis Pharmaceuticals, Inc. (IONS)

$44.12+$1.42 (+3.33%)as of 4:00 PM ET Thu 15 Oct
Live quote as of 4:00 PM ET Thu 15 Oct · previous close $42.70 · source: Finnhub
Quarterly revenue
$267.9M
-40.7% vs. a year earlier · Quarter ended 30 Jun 2026
YTD -44.2%1M -1.6%Mkt cap $7.2B52-wk range $42.38–$86.50

What happened

  1. Ionis Pharmaceuticals closed at $44.12 on Thursday, 15 October, up 3.33%. It is down 44.2% this year, 49.0% below its 52-week closing high.
  2. Its latest reported quarter (quarter ended 30 Jun 2026) showed revenue of $267.9M, down 40% from $452.0M, and net income of -$114.6M.
  3. Its most recent 8-K, filed 23 Sep 2026, published a Regulation FD disclosure and disclosed another material event.
  4. Next earnings: Wednesday, 4 November (estimated date); consensus EPS -$1.20.

IONS price chart

IONS daily close, 3 months Source: Yahoo Finance
IONS daily close, 6 months Source: Yahoo Finance
IONS daily close, 1 year · dots mark earnings dates Source: Yahoo Finance; Nasdaq

Key numbers

Revenue (latest quarter)$267.9M-40.7% year over year · Quarter ended 30 Jun 2026
Revenue (last 4 quarters)$874.1M
Net income-$114.6Mdown from $123.6M a year earlier
Diluted EPS-$0.69vs. $0.70 a year earlier
Operating margin-38.2%
Cash & equivalents$350.1Mat 30 Jun 2026
Market cap$7.16BNasdaq
52-week closing range$42.38 – $86.50high on 6 Feb 2026
Latest periodic report10-Qfiled 29 Jul 2026 · period 30 Jun 2026
Next earnings4 Nov 2026*estimated (Zacks via Nasdaq)
IndustryBiotechnology: Pharmaceutical PreparationsHealth Care

Revenue by quarter

$133.8M
Sep '24
$226.6M
Dec '24
$131.6M
Mar '25
$452.0M
Jun '25
$156.7M
Sep '25
$203.3M
Dec '25
$246.1M
Mar '26
$267.9M
Jun '26
Ionis Pharmaceuticals quarterly revenue Source: SEC EDGAR XBRL (Q4 derived where needed)
-$140.5M
Sep '24
-$104.3M
Dec '24
-$146.9M
Mar '25
$123.6M
Jun '25
-$128.6M
Sep '25
-$229.4M
Dec '25
-$92.5M
Mar '26
-$114.6M
Jun '26
Ionis Pharmaceuticals quarterly net income Source: SEC EDGAR XBRL

In the filing

Ionis Pharmaceuticals's latest 10-Q, filed 29 July 2026 for the period ended 30 June 2026, reported revenue of $267.9M, down 40% from $452.0M a year earlier, and 8.9% more than the previous quarter.

Net income was -$114.6M (down from $123.6M). Diluted EPS was -$0.69, against $0.70 a year before. Operating margin was -38.2%. Cash and equivalents stood at $350.1M on 30 Jun 2026.

Read the full 10-Q on SEC.gov · all exhibits

Latest 8-K · 23 Sep 2026

Ionis Pharmaceuticals published a Regulation FD disclosure and disclosed another material event. Read on SEC.gov

Earnings vs. expectations

Reported EPS Consensus
-$0.80
-$1.23
Sep 2025
-$1.41
-$1.31
Dec 2025
-$0.56
-$0.89
Mar 2026
-$0.70
-$1.09
Jun 2026
Ionis Pharmaceuticals: EPS vs. consensus Source: Nasdaq (Zacks)

Recent SEC filings

DateFormWhat it is
23 Sep 20268-KCurrent report: published a Regulation FD disclosure and disclosed another material event
4 Sep 20268-KCurrent report: published a Regulation FD disclosure and disclosed another material event
4 Sep 20268-KCurrent report: published a Regulation FD disclosure and disclosed another material event
29 Jul 202610-QQuarterly report
29 Jul 20268-KCurrent report: reported results of operations
10 Jul 20268-KCurrent report: published a Regulation FD disclosure
9 Jul 20268-KCurrent report: published a Regulation FD disclosure and disclosed another material event
24 Jun 20268-KCurrent report: published a Regulation FD disclosure and disclosed another material event

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