Twist Bioscience (TWST) Latest Stock Analysis Report – Oct 15, 2026, 4:00 PM ET
Updated Oct 15, 2026, 4:00 PM ET
- Closed at $144.49, -2.48% vs the prior close of $148.16.
- Volume 3.54M shares, 1.5x its 50-day average.
- No new SEC filings since the prior session.
- No new insider buys or sales reported since the prior session.
TWST dips 2.5% to $144.49, 4 down days in a row. Closed at $144.49, -2.48% vs the prior close of $148.16. Day range $130.68–$148.32, opened at $138.09.
TWST daily analysis — what happened
A plain-English, data-only note written after every US trading day. Newest first; older days stay archived below.
Oct 15, 2026 — TWST dips 2.5% to $144.49, 4 down days in a row
- Closed at $144.49, -2.48% vs the prior close of $148.16. Day range $130.68–$148.32, opened at $138.09.
- Volume was 3.54M shares, 1.5x its 50-day average of 2.32M.
- Price is -2.0% vs its 50-day average ($147.44) and +74.6% vs its 200-day average ($82.75).
- 52-week range $23.30–$219.71; today's close sits at 62% of that range, 34.2% below the 52-week high.
- That makes 4 straight losses.
Oct 14, 2026 — TWST dips 2.1% to $148.16, 3 down days in a row
- Closed at $148.16, -2.09% vs the prior close of $151.33. Day range $144.79–$156.00, opened at $146.69.
- Volume was 2.11M shares, 0.9x its 50-day average of 2.30M.
- Price is +0.9% vs its 50-day average ($146.85) and +80.3% vs its 200-day average ($82.20).
- 52-week range $23.30–$219.71; today's close sits at 64% of that range, 32.6% below the 52-week high.
- That makes 3 straight losses.
Oct 13, 2026 — TWST dips 0.3% to $151.33
- Closed at $151.33, -0.35% vs the prior close of $151.86. Day range $146.00–$154.23, opened at $149.00.
- Volume was 1.53M shares, 0.7x its 50-day average of 2.33M.
- Price is +3.7% vs its 50-day average ($145.87) and +85.4% vs its 200-day average ($81.62).
- 52-week range $23.30–$219.71; today's close sits at 65% of that range, 31.1% below the 52-week high.
Oct 12, 2026 — TWST slides 5.0% to $151.86
- Closed at $151.86, -4.96% vs the prior close of $159.78. Day range $147.55–$161.80, opened at $159.78.
- Volume was 2.65M shares, 1.1x its 50-day average of 2.31M.
- Price is +4.8% vs its 50-day average ($144.87) and +87.4% vs its 200-day average ($81.03).
- 52-week range $23.30–$219.71; today's close sits at 65% of that range, 30.9% below the 52-week high.
Oct 9, 2026 — TWST jumps 5.1% to $159.78
- Closed at $159.78, +5.08% vs the prior close of $152.05. Day range $152.14–$168.93, opened at $152.69.
- Volume was 3.54M shares, 1.6x its 50-day average of 2.27M.
- Price is +11.2% vs its 50-day average ($143.66) and +98.6% vs its 200-day average ($80.44).
- 52-week range $23.30–$219.71; today's close sits at 69% of that range, 27.3% below the 52-week high.
Oct 8, 2026 — TWST dips 2.3% to $152.05 on 2.0x normal volume
- Closed at $152.05, -2.31% vs the prior close of $155.65. Day range $144.60–$152.59, opened at $148.00.
- Volume was 4.37M shares, 2.0x its 50-day average of 2.21M — unusually heavy trading.
- Price is +6.9% vs its 50-day average ($142.29) and +90.5% vs its 200-day average ($79.82).
- 52-week range $23.30–$219.71; today's close sits at 66% of that range, 30.8% below the 52-week high.
- That makes 3 straight losses.
Oct 7, 2026 — TWST slides 6.8% to $155.65 on 2.8x normal volume
- Closed at $155.65, -6.78% vs the prior close of $166.97. Day range $152.50–$167.44, opened at $158.26.
- Volume was 5.90M shares, 2.8x its 50-day average of 2.12M — unusually heavy trading.
- Price is +10.4% vs its 50-day average ($140.96) and +96.5% vs its 200-day average ($79.22).
- 52-week range $23.30–$219.71; today's close sits at 67% of that range, 29.2% below the 52-week high.
Oct 6, 2026 — TWST slides 18.6% to $166.97 on 4.3x normal volume
- Closed at $166.97, -18.55% vs the prior close of $205.00. Day range $164.49–$219.71, opened at $209.55.
- Volume was 8.56M shares, 4.3x its 50-day average of 1.98M — unusually heavy trading.
- Price is +19.6% vs its 50-day average ($139.62) and +112.4% vs its 200-day average ($78.60).
- 52-week range $23.30–$219.71; today's close sits at 73% of that range, 24.0% below the 52-week high.
Oct 5, 2026 — TWST jumps 8.7% to $205.00, a 52-week high
- Closed at $205.00, +8.66% vs the prior close of $188.67. Day range $189.25–$207.90, opened at $193.46.
- Volume was 3.21M shares, 1.7x its 50-day average of 1.93M.
- Price is +48.5% vs its 50-day average ($138.01) and +163.1% vs its 200-day average ($77.93).
- 52-week range $23.30–$207.90; today's close sits at 98% of that range, 1.4% below the 52-week high.
Oct 2, 2026 — TWST rises 0.3% to $188.67
- Closed at $188.67, +0.33% vs the prior close of $188.05. Day range $183.39–$198.10, opened at $188.76.
- Volume was 2.08M shares, 1.1x its 50-day average of 1.92M.
- Price is +39.0% vs its 50-day average ($135.71) and +144.8% vs its 200-day average ($77.06).
- 52-week range $23.30–$200.31; today's close sits at 93% of that range, 5.8% below the 52-week high.
TWST latest news & SEC filings
Every SEC filing by or about TWST in the last 120 days, explained in plain English. Updated daily, with a same-day refresh for new filings.
Oct 13, 2026 · 4 — Insider trade report (Form 4)
Insider trade report (Form 4) — a director, officer or 10%+ owner changed their holdings
- Laponis Adam sold 2,462 shares at $156.30 (≈$384.82K) on Oct 9, 2026; now holds 98,114
Open-market purchases (P) and sales (S) are shown in colour; awards, exercises and tax withholding are routine pay-related moves. Many sales are pre-planned under 10b5-1 plans.
Oct 9, 2026 · 144 — Notice of proposed sale (Form 144)
Notice of proposed sale (Form 144) — an insider or affiliate plans to sell restricted or control shares
A notice of intent, not a completed sale. Any actual sale by a director or officer shows up later on Form 4.
Oct 7, 2026 · 4 — Insider trade report (Form 4)
Insider trade report (Form 4) — a director, officer or 10%+ owner changed their holdings
- Leproust Emily M. sold 1,840 shares at $200.44 (≈$368.81K) on Oct 5, 2026; now holds 565,468
- Leproust Emily M. sold 481 shares at $201.26 (≈$96.80K) on Oct 5, 2026; now holds 564,987
- Leproust Emily M. sold 1,017 shares at $202.32 (≈$205.76K) on Oct 5, 2026; now holds 563,970
- Leproust Emily M. sold 432 shares at $203.61 (≈$87.96K) on Oct 5, 2026; now holds 563,538
- Leproust Emily M. sold 290 shares at $204.80 (≈$59.39K) on Oct 5, 2026; now holds 563,248
- Leproust Emily M. sold 297 shares at $205.78 (≈$61.12K) on Oct 5, 2026; now holds 562,951
- …plus 2 more transaction lines in the filing.
Open-market purchases (P) and sales (S) are shown in colour; awards, exercises and tax withholding are routine pay-related moves. Many sales are pre-planned under 10b5-1 plans.
Oct 5, 2026 · 144 — Notice of proposed sale (Form 144)
Notice of proposed sale (Form 144) — an insider or affiliate plans to sell restricted or control shares
A notice of intent, not a completed sale. Any actual sale by a director or officer shows up later on Form 4.
Oct 5, 2026 · 4 — Insider trade report (Form 4)
Insider trade report (Form 4) — a director, officer or 10%+ owner changed their holdings
- Laponis Adam sold 8,057 shares at $188.88 (≈$1.52M) on Oct 2, 2026; now holds 100,576
Open-market purchases (P) and sales (S) are shown in colour; awards, exercises and tax withholding are routine pay-related moves. Many sales are pre-planned under 10b5-1 plans.
Oct 5, 2026 · 4 — Insider trade report (Form 4)
Insider trade report (Form 4) — a director, officer or 10%+ owner changed their holdings
- Green Paula sold 10,088 shares at $188.88 (≈$1.91M) on Oct 2, 2026; now holds 106,632
Open-market purchases (P) and sales (S) are shown in colour; awards, exercises and tax withholding are routine pay-related moves. Many sales are pre-planned under 10b5-1 plans.
Sep 8, 2026 · SCHEDULE 13G/A — Update to a passive 5%+ stake (13G)
Update to a passive 5%+ stake (13G)
Filed by an outside investor (not the company). It reports a holding of more than 5% of a share class; percentage and holder name are in the filing.
Sep 8, 2026 · SCHEDULE 13G/A — Update to a passive 5%+ stake (13G)
Update to a passive 5%+ stake (13G)
Filed by an outside investor (not the company). It reports a holding of more than 5% of a share class; percentage and holder name are in the filing.
Aug 19, 2026 · 8-K — Current report
Current report — a filing companies must make within 4 business days of a major event
- Item 8.01 — Reported other events the company considers important.
Aug 19, 2026 · 424B7 — Prospectus supplement for a resale by holders
Prospectus supplement for a resale by holders
An offering document: new shares or debt may be sold, which can increase the share count (dilution) or debt load. Size and terms are in the prospectus.
Aug 19, 2026 · 8-K — Current report
Current report — a filing companies must make within 4 business days of a major event
- Item 7.01 — Released information under Regulation FD (e.g. a presentation or press release).
Aug 14, 2026 · SCHEDULE 13G/A — Update to a passive 5%+ stake (13G)
Update to a passive 5%+ stake (13G)
Filed by an outside investor (not the company). It reports a holding of more than 5% of a share class; percentage and holder name are in the filing.
Aug 14, 2026 · SCHEDULE 13G — Passive stake (13G)
Passive stake (13G) — an investor reported owning more than 5%
Filed by an outside investor (not the company). It reports a holding of more than 5% of a share class; percentage and holder name are in the filing.
Aug 14, 2026 · SCHEDULE 13G/A — Update to a passive 5%+ stake (13G)
Update to a passive 5%+ stake (13G)
Filed by an outside investor (not the company). It reports a holding of more than 5% of a share class; percentage and holder name are in the filing.
Aug 13, 2026 · SCHEDULE 13G/A — Update to a passive 5%+ stake (13G)
Update to a passive 5%+ stake (13G)
Filed by an outside investor (not the company). It reports a holding of more than 5% of a share class; percentage and holder name are in the filing.
Things to know before you trade TWST
- Last results release: Aug 3, 2026 (8-K Item 2.02). Previous ones: May 4, 2026, Feb 2, 2026, Jan 12, 2026. Based on that rhythm, the next report is likely around Nov 2, 2026 — an estimate, not a confirmed date.
- How much it moves: over the last 20 sessions the average daily move was 4.64% (largest 18.6%). That is a volatile stock.
- Liquidity: about 3.29M shares (≈$474.84M) trade per day on average.
- 52-week position: $144.49 vs a range of $23.30–$219.71 (62% of the range).
- Dividends: no cash dividends in the last 2 years.
- Splits: none in the last 2 years.
- Insider trades (Form 4, last 12 months, recent 25 shown): 0 open-market buys, 25 sales; latest: Emily M. Leproust sold 16 shares on Sep 24, 2026.
- Latest filings: 8-K Aug 19, 2026; 8-K Aug 19, 2026; 8-K Aug 5, 2026.
- Share count: 62.71M shares outstanding (Jul 29, 2026), +3.9% vs a year earlier.
- Listing: Nasdaq · industry: Biological Products, (No Diagnostic Substances).
TWST market data (last 20 sessions)
| Date | Open | High | Low | Close | Volume |
|---|---|---|---|---|---|
| Oct 15, 2026 | 138.09 | 148.32 | 130.68 | 144.49 | 3.54M |
| Oct 14, 2026 | 146.69 | 156.00 | 144.79 | 148.16 | 2.11M |
| Oct 13, 2026 | 149.00 | 154.23 | 146.00 | 151.33 | 1.53M |
| Oct 12, 2026 | 159.78 | 161.80 | 147.55 | 151.86 | 2.65M |
| Oct 9, 2026 | 152.69 | 168.93 | 152.14 | 159.78 | 3.54M |
| Oct 8, 2026 | 148.00 | 152.59 | 144.60 | 152.05 | 4.37M |
| Oct 7, 2026 | 158.26 | 167.44 | 152.50 | 155.65 | 5.90M |
| Oct 6, 2026 | 209.55 | 219.71 | 164.49 | 166.97 | 8.56M |
| Oct 5, 2026 | 193.46 | 207.90 | 189.25 | 205.00 | 3.21M |
| Oct 2, 2026 | 188.76 | 198.10 | 183.39 | 188.67 | 2.08M |
| Oct 1, 2026 | 193.10 | 200.31 | 187.60 | 188.05 | 3.12M |
| Sep 30, 2026 | 188.75 | 197.19 | 187.05 | 193.24 | 3.25M |
| Sep 29, 2026 | 179.90 | 190.76 | 179.73 | 186.13 | 3.68M |
| Sep 28, 2026 | 181.82 | 187.87 | 175.02 | 179.60 | 2.20M |
| Sep 25, 2026 | 184.03 | 186.20 | 177.39 | 182.83 | 2.71M |
| Sep 24, 2026 | 157.72 | 185.22 | 156.83 | 184.03 | 3.53M |
| Sep 23, 2026 | 164.35 | 166.35 | 157.41 | 158.50 | 2.13M |
| Sep 22, 2026 | 165.83 | 170.66 | 162.86 | 164.60 | 2.31M |
| Sep 21, 2026 | 168.40 | 170.23 | 160.62 | 165.83 | 2.24M |
| Sep 18, 2026 | 158.04 | 167.05 | 156.16 | 166.99 | 3.07M |
About Twist Bioscience
Twist Bioscience (TWST) is listed on the Nasdaq and classified by the SEC under “Biological Products, (No Diagnostic Substances)”. Its business address is in SOUTH SAN FRANCISCO, CA. State of incorporation: DE. Fiscal year ends September 30. SEC CIK 1581280.
TWST board of directors & executives
From SEC Form 3/4/5 insider filings made in the last 12 months (date = latest filing).
Directors
| Name | Role | Latest filing |
|---|---|---|
| Katryn Blake | Director | Aug 14, 2026 |
| Robert Chess | Director | Aug 11, 2026 |
| Keith Crandell | Director | Feb 9, 2026 |
| Nelson Chan | Director | Feb 9, 2026 |
| Jan Johannessen | Director | May 14, 2026 |
| Emily M. Leproust | Chief Executive Officer | Sep 25, 2026 |
| Robert P Ragusa | Director | Feb 9, 2026 |
| Melissa A. Starovasnik | Director | Jun 1, 2026 |
Executive officers
| Name | Title | Latest filing |
|---|---|---|
| Dennis Cho | See Remarks | Sep 23, 2026 |
| Patrick John Finn | President and COO | Aug 25, 2026 |
| Paula Green | SVP of Human Resources | Sep 23, 2026 |
| Adam Laponis | Chief Financial Officer | Aug 25, 2026 |
| Emily M. Leproust | Chief Executive Officer | Sep 25, 2026 |
| Robert F. Werner | Chief Accounting Officer | Sep 10, 2026 |
Recent insider buys & sales
| Date | Insider | Type | Shares | Price |
|---|---|---|---|---|
| Sep 24, 2026 | Emily M. Leproust | Sale | 16 | $182.50 |
| Sep 24, 2026 | Emily M. Leproust | Sale | 501 | $183.76 |
| Sep 24, 2026 | Emily M. Leproust | Sale | 21 | $181.45 |
| Sep 24, 2026 | Emily M. Leproust | Sale | 515 | $180.39 |
| Sep 24, 2026 | Emily M. Leproust | Sale | 143 | $179.93 |
| Sep 24, 2026 | Emily M. Leproust | Sale | 330 | $178.67 |
| Sep 24, 2026 | Emily M. Leproust | Sale | 164 | $177.17 |
| Sep 24, 2026 | Emily M. Leproust | Sale | 945 | $176.39 |
| Sep 24, 2026 | Emily M. Leproust | Sale | 2,485 | $175.23 |
| Sep 24, 2026 | Emily M. Leproust | Sale | 83 | $184.60 |
| Sep 21, 2026 | Dennis Cho | Sale | 348 | $165.49 |
| Sep 21, 2026 | Emily M. Leproust | Sale | 1,687 | $165.49 |
| Sep 21, 2026 | Paula Green | Sale | 294 | $165.49 |
| Sep 17, 2026 | Emily M. Leproust | Sale | 4,175 | $154.17 |
| Sep 17, 2026 | Emily M. Leproust | Sale | 2,565 | $162.31 |
TWST financials (annual, from XBRL filings)
| Fiscal year end | Revenue | Net income | Diluted EPS | Operating cash flow |
|---|---|---|---|---|
| Sep 30, 2025 | — | $-77.67M | -1.30 | $-47.63M |
| Sep 30, 2024 | — | $-208.73M | -3.60 | $-64.09M |
| Sep 30, 2023 | — | $-204.62M | -3.60 | $-142.47M |
| Sep 30, 2022 | — | $-217.86M | -4.04 | $-124.39M |
| Sep 30, 2021 | — | $-152.10M | -3.15 | $-112.24M |
Latest balance sheet: total assets $672.44M, total liabilities $226.70M, cash $117.44M (as of Jun 30, 2026).
TWST earnings / results-day log
| Date | Filing | Close that day |
|---|---|---|
| Aug 3, 2026 | 8-K Item 2.02 (results) | $101.06 |
| May 4, 2026 | 8-K Item 2.02 (results) | $56.19 |
| Feb 2, 2026 | 8-K Item 2.02 (results) | $46.81 |
| Jan 12, 2026 | 8-K Item 2.02 (results) | $38.04 |
| Nov 14, 2025 | 8-K Item 2.02 (results) | $26.87 |
| Aug 4, 2025 | 8-K Item 2.02 (results) | $30.21 |
| May 5, 2025 | 8-K Item 2.02 (results) | $35.93 |
| Feb 3, 2025 | 8-K Item 2.02 (results) | $52.75 |
| Nov 18, 2024 | 8-K Item 2.02 (results) | $41.43 |
| Aug 2, 2024 | 8-K Item 2.02 (results) | — |
| May 2, 2024 | 8-K Item 2.02 (results) | — |
| Feb 2, 2024 | 8-K Item 2.02 (results) | — |
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Information only, not investment advice. BuyMeWhiskey is not a registered investment adviser or broker-dealer; nothing here is a recommendation to buy, sell or hold any security, and there are no price targets. Data comes from SEC EDGAR filings and public end-of-day market data and may be delayed or contain errors. Verify with the company's filings before making decisions. Prices: end-of-day data as of Oct 15, 2026, 4:00 PM ET. Filings: SEC EDGAR. Updated after every US trading day.