Quick answer
Registered Nurses in South Carolina earned a median of $82,360 a year ($39.60 an hour) in May 2025, 16% below the national median of $97,550; 49,750 were employed there, ranking #40 of 53 states and territories by median pay, per BLS OEWS.
Data as of May 2025. Source: U.S. Bureau of Labor Statistics, OEWS May 2025
| Measure | South Carolina | United States |
|---|---|---|
| Median annual wage | $82,360 | $97,550 |
| Mean annual wage | $87,670 | $101,420 |
| Median hourly wage | $39.60 | $46.90 |
| 10th percentile | $66,860 | $68,940 |
| 25th percentile | $77,320 | $80,330 |
| 75th percentile | $97,230 | $112,350 |
| 90th percentile | $106,520 | $137,470 |
| Employment | 49,750 | 3,379,720 |
| Jobs per 1,000 | 21.583 | — |
| Location quotient | 0.99 | 1.00 |
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Last updated 2026-10-16. Data only, not financial or tax advice.